Tip of the Week – Beyond Use Dating

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All compounded products are susceptible to microbial contamination. Temperature changes and time will contribute to microbial colonization. NAPRA Model Standards for Pharmacy Compounding of Non-Hazardous Sterile Preparation states: “After an initial or stationary phase (phase 1), which varies by species, bacteria replicate within 20 to 30 minutes (phase 2 growth). Once contamination occurs, bacterial growth increases rapidly starting 6 hours after the onset of contamination.”

That’s why applying the correct beyond use date is so important! Beyond use dates are determined by considering the contamination risk of a product. For more information on Beyond Use Dating, as well as some handy charts you can use to help you determine what beyond use date to use, check out the NAPRA Model Standards for Pharmacy Compounding of Non-Hazardous Sterile Preparation.

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